Zeaxanthin

Table of Contents

What is Zeaxanthin?

Zeaxanthin is a carotenoid, a class of pigments found in various plants, algae, and some microorganisms. It is one of the two major carotenoids (along with lutein) that make up the macular pigment of the human eye. Zeaxanthin is known for its role in supporting eye health, particularly in protecting the eyes from the harmful effects of high-energy light, especially ultraviolet (UV) rays.

What are the Benefits of Zeaxanthin?

Zeaxanthin offers several health benefits, primarily due to its role in supporting eye health. Here are some key ways in which zeaxanthin benefits health:

Eye Health:
- Protection Against Blue Light: Zeaxanthin, along with lutein, is concentrated in the macula of the retina. Together, they act as a natural filter for high-energy light, particularly the harmful blue light and ultraviolet (UV) rays. This helps protect the eyes from oxidative damage and reduces the risk of age-related macular degeneration (AMD) and other vision-related issues.
Prevention of Age-Related Macular Degeneration (AMD):
- Zeaxanthin has been associated with a reduced risk of AMD, a progressive eye disease that can lead to central vision loss. AMD is a leading cause of vision impairment in older adults.
Visual Function:
- Zeaxanthin, when present in the macula, contributes to improvements in visual function. This includes factors such as contrast sensitivity, glare recovery, and overall visual acuity, all of which are important for clear vision.
Antioxidant Properties:
- Zeaxanthin acts as an antioxidant, helping to neutralize free radicals in the body. Free radicals are reactive molecules that can contribute to oxidative stress and damage cells. Antioxidants play a crucial role in maintaining overall health and reducing the risk of chronic diseases.
Cognitive Health:
- While more research is needed, some studies suggest a potential link between carotenoids like zeaxanthin and cognitive health. Antioxidants may have protective effects on the brain and could contribute to maintaining cognitive function as individuals age.

What happens if I don’t get enough Zeaxanthin (Deficiency)?

Here are some potential consequences of not getting enough zeaxanthin:

Increased Risk of Age-Related Macular Degeneration (AMD):
- Zeaxanthin, along with lutein, is concentrated in the macula of the retina, where it helps protect the eyes from oxidative damage. Low levels of zeaxanthin, along with lutein, have been associated with an increased risk of AMD, a degenerative eye disease that affects the central part of the retina and can lead to vision loss.
Reduced Visual Function:
- Inadequate intake of zeaxanthin may contribute to reduced visual function, including issues related to contrast sensitivity and glare recovery. These aspects of visual function are important for clear vision, especially in varying light conditions.

While zeaxanthin deficiency itself is not a recognized medical condition, it’s important to highlight the role of zeaxanthin, along with lutein, in maintaining eye health.

Best Food Sources for Zeaxanthin

Zeaxanthin is found in various fruits and vegetables, particularly those with vibrant yellow, orange, and red colors. Including a variety of these foods in your diet can help ensure an adequate intake of zeaxanthin. Here are some of the best food sources for zeaxanthin:

Corn:
- Corn, especially yellow corn, is a good source of zeaxanthin.
Orange Bell Peppers:
- Orange bell peppers contain zeaxanthin and can be enjoyed raw in salads, stir-fries, or as a snack.
Squash:
- Yellow and orange squashes, such as butternut squash and acorn squash, are rich in zeaxanthin.
Egg Yolks:
- Egg yolks contain zeaxanthin, making eggs a dietary source of this carotenoid.
Kiwi:
- Kiwi, particularly the green and gold varieties, contains zeaxanthin along with other nutrients.
Grapes:
- Grapes, especially the red and purple varieties, contain zeaxanthin and other antioxidants.
Spinach:
- While spinach is more well-known for its lutein content, it also contains zeaxanthin.
Kale:
- Kale is a leafy green vegetable that provides both zeaxanthin and lutein.
Collard Greens:
- Collard greens are another leafy green that contributes to zeaxanthin intake.
Turnip Greens:
- Turnip greens are leafy vegetables that contain zeaxanthin and other beneficial nutrients.

It’s important to note that cooking methods can affect the bioavailability of zeaxanthin. Light cooking or sautéing vegetables with a small amount of healthy fat can enhance the absorption of carotenoids, including zeaxanthin.

Zeaxanthin Interaction with Medications / Overconsumption

Zeaxanthin is generally considered safe when obtained from food sources, and it is a naturally occurring pigment found in various fruits and vegetables. However, as with any nutrient, excessive intake through supplements may have potential adverse effects. Here are some considerations regarding the effects of excess zeaxanthin:

Skin Discoloration:
- High doses of zeaxanthin supplements may lead to skin discoloration known as carotenodermia. This is a benign condition where the skin takes on a yellow-orange tint. Carotenodermia is generally reversible and not associated with serious health concerns.
Digestive Issues:
- Excessive intake of zeaxanthin supplements might cause digestive issues in some individuals, such as nausea or upset stomach.
Interaction with Medications:
- Zeaxanthin supplements are generally considered safe for most people when taken at recommended doses. However, it’s essential to be cautious about potential interactions with certain medications. Specifically, zeaxanthin supplements might interfere with anticoagulant medications (blood thinners) because high doses of antioxidants can have antiplatelet effects. If you are taking medications or have concerns about potential interactions, it’s advisable to consult with a healthcare professional before starting zeaxanthin supplements.
Increased Risk of Lung Cancer in Smokers:
- Some studies have suggested that high-dose beta-carotene supplements, a carotenoid related to zeaxanthin, may increase the risk of lung cancer in smokers. While zeaxanthin is not beta-carotene, it’s still advisable for smokers to exercise caution with high-dose supplements.

It’s important to note that adverse effects are more likely to occur with excessive intake of zeaxanthin from supplements rather than through a normal diet rich in fruits and vegetables.